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About 10% to 15% of actinic keratoses eventually change into squamous cell cancers of the skin.

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Secondly, imiquimod use causes inflammation in the skin, which itself may aid in clearing the lesion.

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Treatment of melanoma (that is, lesions 2 mm in thickness or less) consists of surgical removal of the melanoma and removal of 1 cm to 2 cm of normal skin surrounding it, depending on the thickness of the melanoma (called the "").

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