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The most common cause of fetal heart failure is sustained supraventricular tachycardia, which is treated by administering digoxin to the mother.

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To put it differently generics have identical active ingredients and their pharmacological effects are the same, as those of their brand-name equivalents.

Safety and effectiveness of bisoprolol fumarate and hydrochlorothiazide in pediatric patients have not been established.

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Following oral administration, bisoprolol is almost completely absorbed and undergoes minimal first-pass metabolism (less than 20%), resulting in an oral biovailability of about 90%.

Both regimens equally affected blood pressure, during both the monotherapy and combined-therapy phases, whereas bisoprolol-first treatment had a more pronounced heart rate-lowering effect during the monotherapy phase, with similar effect of both regimens at the end of the combined phase ().

One patient had suppression of violent behaviors with persistence of minor behaviors (such as minor limb twitching and vocalizations) at a dose of 50 mg nightly; 1 patient had suppression of RBD symptoms for only 3 weeks, despite doses up to 250 mg nightly and eventually required treatment with clonazepam; and 1 patient was unable to tolerate desipramine.

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Advantages of controlled-release formulations may include extended activity of the drug, reduced dosage frequency, and increased patient compliance.

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In addition, when used in fixed-combination with hydrochlorothiazide, consider the cautions, precautions, and contraindications associated with thiazide diuretics.

These values do not represent the thermodynamic solubility, instead approximately 300 mg bisoprolol fumarate was added to 50 mL buffer.

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This drug sequence seems to result largely from the fact that, historically, the beneficial effects of ACE inhibitors were documented first.

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Clonazepam is suggested for the treatment of RBD but should be used with caution in patients with dementia, gait disorders, or concomitant OSA.

Racemic adrenaline works by stimulation of the alpha adrenergic receptors in the airway, with resultant mucosal vasoconstriction and decreased subglottic edema, and by stimulation of the β adrenergic receptors, with resultant relaxation of the bronchial smooth muscle.

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BB use is strongly recommended in all current guidelines for patient with symptomatic HF and impaired systolic function, unless there is a contraindication.

The highest dose strength of bisoprolol recommended in the 18th edition of the WHO Model List of Essential Medicine is 10 mg for coated tablets.

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Points were provided for the following criteria: manuscript type (abstract, peer-reviewed paper); population size studied (large retrospective study, small case series, case report); explicitly stated dosage timing; identification of peak symptoms related to time of medication administration (i.

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The other receptors elicit a variety of responses in the body, and their blockage could cause a wide range of reactions, but β 1 adrenoreceptors are cardiospecific for the most part, making bisoprolol ideal for treatment of cardiac events.

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